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BACTRIM

BACTRIM


Generic name: Co-trimoxazole Oral (Sulfamethoxazole + Trimethoprim)
Manufacturer : Hoffmann-LaRoche, Inc

What is Bactrim ?
Bactrim , Co-trimoxazole ( sulfamethoxazole and trimethoprim ) is a combination of trimethoprim and sulfamethoxazole, a sulfa drug. It eliminates bacteria that cause various infections, including infections of the urinary tract, lungs (pneumonia), ears, and intestines. It also is used to treat 'travelers' diarrhea.' Antibiotics will not work for colds, flu, or other viral infections.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should Bactrim be used?
Co-trimoxazole comes as a tablet and a liquid to take by mouth. It usually is taken two times a day but may be taken up to four times a day for severe lung infections.
Take each dose with a full glass of water.
Take Co-trimoxazole with food or milk if it upsets your stomach.

You may crush the tablets and put them in water or a soft food like applesauce or pudding if you cannot swallow them whole.

To ensure that you get a correct dose, measure the liquid form of Co-trimoxazole with a special dose-measuring spoon or cup, not with a regular tablespoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Shake the suspension well before measuring a dose.

Take all of the Co-trimoxazole that has been prescribed for you even if you begin to feel better. Your symptoms may start to improve before the infections is completely treated.

What special precautions should I follow?
Before taking co-trimoxazole,
- tell your doctor and pharmacist if you are allergic to co-trimoxazole, diuretics ('water pills', oral diabetes medications, any sulfa drug, or any other drugs.
- tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially methotrexate, phenytoin (Dilantin), warfarin (Coumadin), and vitamins.
- tell your doctor if you have or have ever had liver or kidney disease, asthma, severe allergies, or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease).
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking co-trimoxazole, call your doctor.
- plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Co-trimoxazole may make your skin sensitive to sunlight.

What special dietary instructions should I follow?
Co-trimoxazole may cause an upset stomach. Take co-trimoxazole with food.

Possible drug interactions when taking Bactrim

If Bactrim is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Bactrim with the following:

Amantadine (Symmetrel)
Blood thinners such as Coumadin
Cyclosporine (Neoral, Sandimmune)
Digoxin (Lanoxin)
Indomethacin (Indocin)
Methotrexate (Rheumatrex)
Oral diabetes medications such as Micronase and Glucotrol
Pyrimethamine (Daraprim)
Seizure medications such as Dilantin
Tricyclic antidepressants such as Elavil, Norpramin, Sinequan, and Tofranil
Water pills (diuretics) such as HydroDIURIL


Special information if you are pregnant or breastfeeding
Bactrim should not be taken during pregnancy. If you are pregnant or plan to become pregnant, notify your doctor immediately. Bactrim does appear in breast milk and could affect a nursing infant. It should not be taken while breastfeeding.

What should I do if I forget a dose?
Take the missed dose as soon as you remember. However, if it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose. Do not take a double dose of this medication to make up for a missed one.unless otherwise directed by your doctor.
If you have only missed one dose, you can take the rest of your scheduled doses for that day at evenly spaced intervals.

What happens if I overdose?

Symptoms of a co-trimoxazole overdose include nausea, vomiting, decreased appetite, diarrhea, headache, yellowing of the skin or eyes, decreased urine production, bloody urine, and coma.

What side effects can Bactrim cause?
Although side effects from co-trimoxazole are not common, they can occur. Tell your doctor if any of these symptoms are severe or do not go away:
- upset stomach
- vomiting
- loss of appetite

If you experience any of the following symptoms, call your doctor immediately:

- skin rash
- itching
- sore throat
- fever or chills
- mouth sores
- unusual bruising or bleeding
- yellowing of the skin or eyes
- paleness
- joint aches

What storage conditions are needed for Bactrim?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

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